Early modelling to evaluate price potential and HTA strategy

Case Study
We developed early cost-effectiveness models, perform scenario analyses, and update evidence strategies to guide HTA submissions and optimize pricing potential.
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Technical Ability

We are technically astute, with experts who bring deep healthcare strategy and clinical knowledge to every project.

Early model

We developed an early cost-effectiveness Markov model using the FIECON Model Builder to estimate the cost per QALY of the product compared to other LTP treatments from a health system perspective over a lifetime.

Scenario analysis

The model allowed users to explore cost-effectiveness drivers by adjusting structural settings (e.g., treatment sequence, usage, discontinuation), population subgroups, and cost/clinical inputs.

HTA strategy

We conducted a critical appraisal of comparator models to test key assumptions based on precedents in HTA submissions.

Practical Agility

We are practically agile, operating with a lean structure that allows seamless teamwork and swift resource deployment, ensuring efficient project completion without unnecessary bureaucracy.

Evidence generation strategy

We performed one-way sensitivity analyses and value of information analyses, providing targeted recommendations for evidence generation based on limited data.

Continual model update

We continuously updated the model using available clinical data and pivotal trial evidence for key comparators.

Relevant resources

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